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Updated: Oct 23, 2025
The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
Published on: January 31, 2025
A Prospective Evaluation of Intraoperative Indocyanine Green Fluorescence Angiography for Soft Tissue Sarcomas
Benjamin K Wilke1, Douglas S Schultz, Maria T Huayllani
1From the Department of Orthopedic Surgery (Dr. Wilke, Dr. Schultz, Dr. Sherman, Dr. Murray, Dr. Forte), the Division of Plastic Surgery (Dr. Huayllani, Dr. Boczar, Dr. Forte); and the Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery (Dr. Huayllani, Dr. Boczar, Dr. Spaulding, Dr. Forte), Mayo Clinic, Jacksonville, Florida.
Introduction:
Postoperative wound complications after resection of soft-tissue sarcomas are challenging. Indocyanine green (ICG) angiography has previously been used to predict wound complications, but not for soft-tissue sarcomas. We aimed to evaluate whether this technology could help lower wound complications after soft-tissue sarcoma resections.
Materials And Methods:
We conducted a prospective study from 10/2017 to 9/2019 using ICG angiography during sarcoma resection surgery. Rates of wound complications were compared with a historical control consisting of surgeries before utilization of ICG angiography.
Results:
A total of 88 patients were included in the study. We found significantly lower rates of infection (11.8% versus 38%; P = 0.03) and wound dehiscence (11.8% versus 42.3%; P = 0.02) in the ICG angiography cohort compared with the historical controls.
Conclusion:
ICG angiography use during soft-tissue sarcoma resections is promising technology and warrants further investigation to help reduce postoperative complications.
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