Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulmonary Tuberculosis IV

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Sociodemographic and health-related factors associated with viral load non-suppression and body mass index in adults with depression symptoms receiving antiretroviral therapy in South Africa.

PloS one·2026

Same author

Erratum: Time to Include Vestibular Neurology as a Core Competency for Neurology Trainees.

Neurology. Education·2025

Same author

Time to Include Vestibular Neurology as a Core Competency for Neurology Trainees.

Neurology. Education·2025

Same author

Sociodemographic and health-related factors associated with viral load non-suppression and body mass index in adults with depression symptoms receiving antiretroviral therapy in South African primary care: secondary analysis of randomised trial data.

medRxiv : the preprint server for health sciences·2025

Same author

Understanding the cost-utility of implementing HIV self-testing with digital-based supports.

Frontiers in public health·2025

Same author

A consensus statement on dual purpose pathogen surveillance systems: The always on approach.

PLOS global public health·2024

Search research articles

Related Experiment Video

Updated: Oct 23, 2025

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

Diagnostic testing holds the key to NTD elimination.

Catharina Boehme¹, Sergio Carmona¹, Sarah Nogaro¹

¹FIND, Geneva, Switzerland.

Plos Neglected Tropical Diseases

|August 19, 2021

Summary

Developing fit-for-purpose diagnostic tests is crucial for global neglected tropical disease (NTD) control. Enhanced collaboration and country-level action are vital to accelerate progress and overcome challenges in NTD diagnostics.

More Related Videos

Matrix-based DNA Extraction for Targeted Next-Generation Sequencing on Decontaminated Sputum Samples

Matrix-based DNA Extraction for Targeted Next-Generation Sequencing on Decontaminated Sputum Samples

Published on: June 6, 2025

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

Related Experiment Videos

Last Updated: Oct 23, 2025

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

Matrix-based DNA Extraction for Targeted Next-Generation Sequencing on Decontaminated Sputum Samples

Matrix-based DNA Extraction for Targeted Next-Generation Sequencing on Decontaminated Sputum Samples

Published on: June 6, 2025

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

Area of Science:

Global Health
Infectious Diseases
Diagnostic Development

Background:

Neglected tropical diseases (NTDs) pose a significant global health burden.
The World Health Organization (WHO) emphasizes "fit-for-purpose" diagnostics for NTD control.
Current diagnostic tools are insufficient for many NTDs, hindering eradication efforts.

Purpose of the Study:

To highlight the critical need for improved and novel diagnostic tests for NTDs.
To underscore the challenges in diagnostic development and implementation for NTDs.
To advocate for a coordinated ecosystem to accelerate NTD diagnostic progress.

Main Methods:

Review of current landscape of NTD diagnostics.
Analysis of challenges hindering diagnostic development and deployment.
Synthesis of recommendations for an improved NTD diagnostic ecosystem.

Main Results:

Existing diagnostic efforts for NTDs are fragmented and underfunded.
The COVID-19 pandemic has exacerbated systemic weaknesses in global health programs.
Lack of coordination leads to resource duplication and inefficiency.

Conclusions:

A collaborative, country-driven ecosystem is essential for advancing NTD diagnostics.
Prioritizing visibility, creativity, and commitment can accelerate progress towards NTD goals.
Investment in "fit-for-purpose" diagnostics is a prerequisite for NTD prevention and elimination.