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Effect of corticosteroids and aminophylline on active E-rosette formation in patients with diabetic retinopathy
L J Antunes1, C F Barsante, J A Nogueira-Machado
1Departamento de Bioquímica e Immunologia, ICB Universidade Federal de Minas Gerais, UFMG Belo Horizonte, Brazil.
Metabolic, Pediatric, and Systemic Ophthalmology (New York, N.Y. : 1985)
|January 1, 1987
Abstract:
The reactivity of lymphocyte that form active E-rosettes to corticosteroids and aminophylline were examined in diabetic retinopathy patients with normal intraocular pressure. Aminophylline induced a significant activation of active E-rosette formation when compared with normal subjects. Similar results were observed when diabetics' lymphocytes were tested with corticosteroids. These drugs appear to induce an increase of quantity of T11-sheep erythrocyte receptors on T cells, suggesting abnormalities in diabetics' lymphocytes reactivity.