Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

6.2K
The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
6.2K
Phases of Wound Repair01:28

Phases of Wound Repair

6.8K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
6.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Robust Critical Connectivity Threshold in Ranked Percolation of Granular Packings.

Physical review letters·2026
Same author

Rigid m-percolation in limited-valence gels.

Physical review. E·2025
Same author

Structural criterion for the onset of rigidity in a colloidal gel.

Physical review. E·2025
Same author

Healing regimes for microscopic wounds in the vertex model of cell tissues.

Physical review. E·2025
Same author

Lattice model for self-folding at the microscale.

The European physical journal. E, Soft matter·2021
Same author

Modeling of Cell-Mediated Self-Assembled Colloidal Scaffolds.

ACS applied materials & interfaces·2020
Same journal

Erratum: Low-dimensional model for adaptive networks of spiking neurons [Phys. Rev. E 111, 014422 (2025)].

Physical review. E·2026
Same journal

Disentangling the effects of many-body forces on depletion interactions.

Physical review. E·2026
Same journal

Charge transport and mode transition in dual-energy electron beam diodes.

Physical review. E·2026
Same journal

Optimization of multisite reactions in complex compartmentalized media.

Physical review. E·2026
Same journal

Origin of geometric cohesion in nonconvex granular materials: Interplay between interdigitation and rotational constraints enhancing frictional stability.

Physical review. E·2026
Same journal

Interaction of walkers with a standing Faraday wave.

Physical review. E·2026
See all related articles

Related Experiment Video

Updated: Oct 23, 2025

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
07:56

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model

Published on: January 10, 2025

824

Wound opening in a thin incompressible viscoelastic tissue.

G M Carvalho1,2,3, N A M Araújo1,2, P Patrício1,4

  • 1Centro de Física Teórica e Computacional, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.

Physical Review. E
|August 20, 2021
PubMed
Summary
This summary is machine-generated.

Tissue viscoelasticity and friction govern immediate wound opening mechanics. A single dimensionless parameter, lambda, defines deformation regimes based on viscosity versus friction, crucial for understanding early wound healing.

More Related Videos

Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding
08:35

Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding

Published on: February 26, 2015

19.4K
Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography
07:57

Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography

Published on: May 10, 2022

2.3K

Related Experiment Videos

Last Updated: Oct 23, 2025

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
07:56

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model

Published on: January 10, 2025

824
Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding
08:35

Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding

Published on: February 26, 2015

19.4K
Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography
07:57

Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography

Published on: May 10, 2022

2.3K

Area of Science:

  • Biomechanics
  • Materials Science
  • Tissue Engineering

Background:

  • Wound healing initiation involves complex mechanical processes.
  • Understanding early wound mechanics is crucial before biological responses occur.
  • Tissue properties like elasticity, viscosity, and friction play significant roles.

Purpose of the Study:

  • To develop a model for investigating wound opening mechanics in viscoelastic tissues.
  • To analytically and numerically study the immediate post-infliction wound opening process.
  • To identify key parameters governing wound deformation regimes.

Main Methods:

  • Analytical modeling of viscoelastic, isotropic, homogeneous, and incompressible thin tissue.
  • Numerical simulations of wound opening mechanics.
  • Dimensional analysis to define deformation regimes.

Main Results:

  • Wound opening is primarily driven by homeostatic tension, elastic/viscous properties, and friction.
  • A single dimensionless parameter (λ) characterizes deformation regimes for circular wounds.
  • λ quantifies the balance between tissue viscosity and substrate friction.

Conclusions:

  • The model provides insights into the initial mechanical forces driving wound opening.
  • Viscosity and friction are critical factors determining how wounds deform immediately after injury.
  • The dimensionless parameter λ offers a simplified way to understand complex wound mechanics.