Related Experiment Video
Updated: Oct 23, 2025

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
Published on: January 10, 2025
Wound opening in a thin incompressible viscoelastic tissue
G M Carvalho1,2,3, N A M Araújo1,2, P Patrício1,4
1Centro de Física Teórica e Computacional, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.
Abstract:
We develop a model to investigate analytically and numerically the mechanics of wound opening made in a viscoelastic, isotropic, homogeneous, and incompressive thin tissue. This process occurs just immediately after the wound infliction. Before any active biological action has taken place, the tissue relaxes, and the wound opens mostly due to the initial homeostatic tension of the tissue, its elastic and viscous properties, and the existing friction between the tissue and its substrate. We find that for a circular wound the regimes of deformation are defined by a single adimensional parameter λ, which characterizes the relative importance of viscosity over friction.
More Related Videos
Related Concept Videos
Inflammatory Response II: Inflammatory Exudate and Tissue Repair
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
Phases of Wound Repair
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...

