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Destructive soft tissue metastases in advanced colorectal cancer: a case report
Michael S Krasovitsky1, David Goldstein2
1Comprehensive Cancer Centre, Prince of Wales Hospital, Randwick, NSW, Australia; Kinghorn Cancer Centre, St Vincent's Hospital, Darlinghurst, NSW, Australia; Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Randwick, NSW, Australia.
Annals of Palliative Medicine
|August 20, 2021
Summary
Advanced colon cancer can rarely spread to extremity soft tissues, posing a poor prognosis. Whole-body PET scans are crucial for detecting these rare metastases, aiding in management.
Area of Science:
- Oncology
- Radiology
- Surgical Pathology
Background:
- Extremity soft tissue metastases from colon cancer are rare but associated with poor prognosis.
- Limited data exists on the management of these uncommon metastatic sites.
Observation:
- A 76-year-old male with advanced colon adenocarcinoma presented with thigh pain and disfigurement.
- MRI revealed a soft tissue lesion not seen on initial PET scan.
- Whole-body PET confirmed a highly avid lesion, with biopsy confirming metastatic adenocarcinoma.
Findings:
- Extremity soft tissue metastasis from colon cancer can be challenging to detect with standard imaging.
- Whole-body PET scanning may be superior to per-protocol scans for identifying these lesions.
- Management of extremity metastases is complex, with poor locoregional symptom control observed.
Implications:
- Highlights the need to consider extremity soft tissue lesions in advanced colon cancer patients.
- Underscores the utility of whole-body PET scanning for comprehensive staging.
- Emphasizes the need for further research into the incidence and optimal management strategies.
