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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
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Bordetella avium-associated endophthalmitis: case report
BMC Infectious Diseases
|August 20, 2021
Summary
Bordetella avium, a bacterium typically found in birds, can cause severe eye infections in humans. Prompt treatment including surgery and antibiotics is crucial for successful outcomes.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Bordetella avium typically colonizes the respiratory tracts of birds, causing bordetellosis.
- Human infections with B. avium are rare, with few documented cases of ocular involvement.
Observation:
- A case of acute infectious endophthalmitis following open eye trauma is presented.
- The patient presented with symptoms of severe intraocular infection after a traumatic eye injury.
Findings:
- Bordetella avium was identified as the causative agent of the endophthalmitis.
- Nanopore targeted sequencing enabled rapid identification of the B. avium infection.
Implications:
- B. avium can cause severe purulent endophthalmitis in the human eye.
- Successful treatment involves emergency vitrectomy, lens removal, silicone oil tamponade, and early broad-spectrum antibiotics.
- Rapid diagnostic techniques like Nanopore sequencing are vital for managing rare microbial eye infections.

