Related Experiment Videos
Muscarinic receptors in brain from four strains of inbred mice
1Clinical Neurogenetics Branch, National Institute of Mental Health, Bethesda, Maryland 20205.
Neurochemical Research
|December 1, 1987
Abstract:
The density of brain muscarinic receptors from four strains of inbred mice was determined. C57BL/6J mice had a significantly higher density of muscarinic receptors in the forebrain than Balb/cJ or C57BL/10J mice. In the midbrain, C57BL/6J mice also had the highest density of receptors and in the hindbrain, C57BL/6J and AKR/J mice had a two fold higher receptor density compared to the other two strains. These findings demonstrate that inbred strains of mice which exhibit a range of genetically-determined behaviors, have varying densities of muscarinic receptors.