Cardiac MR images of thalassemia major patients with myocardial iron overload: a data note

Area of Science:

• Cardiology
• Radiology
• Medical Imaging

Background:

• Thalassemia major (TM) patients face high mortality from heart failure due to myocardial iron overload.
• T2* weighted MR imaging is the gold standard for assessing iron overload.

Purpose of the Study:

• To provide a dataset of cardiac MR images and clinical data for TM patients and controls.
• To facilitate research on myocardial iron overload and early heart failure prediction in TM.
• To support medical image processing tasks like ventricle segmentation.

Main Methods:

• Open-source cardiac MR images (16-bit grayscale, DICOM) from 50 subjects (TM patients and controls).
• Clinical and echocardiographic data were collected between February 2016 and January 2019.
• Images are anonymized and compressed in RAR format.

Main Results:

• Dataset includes cardiac MR images and associated clinical/echocardiographic data.
• Data is suitable for investigating myocardial iron overload in thalassemia major.
• Enables research into cardiac function and heart failure prediction.

Conclusions:

• This dataset is valuable for researchers studying myocardial iron overload in thalassemia major.
• The data can be utilized for developing and testing medical image analysis algorithms.
• Facilitates advancements in early heart failure detection and management for TM patients.