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Breathlessness and Respiratory Disability After Kidney Transplantation.
Anthony O'Riordan1, Aisling Farrell1, Nouh Baqer1
1The Department of Respiratory Medicine, Cork University Hospital, Cork, Ireland.
Transplantation Proceedings
|August 20, 2021
Summary
Many kidney transplant recipients experience breathlessness. A significant number require respiratory assessment, indicating a need for pre-transplant pulmonological evaluation to improve patient outcomes.
Area of Science:
- Nephrology
- Pulmonology
- Transplantation Medicine
Background:
- Dyspnea (shortness of breath) is a frequent complaint among patients with end-stage kidney disease undergoing dialysis.
- Kidney transplantation aims to improve patient survival and quality of life.
Purpose of the Study:
- To assess the prevalence of respiratory disability in kidney allograft recipients post-transplantation.
- To identify respiratory compromise as a potential target for therapeutic intervention in this population.
Main Methods:
- A cohort of 103 kidney transplant recipients participated in this prevalence study.
- Participants completed the Medical Research Council (MRC) dyspnea scale and St George's Respiratory Questionnaire.
- Basic spirometry was performed, with further assessment by a respiratory physician if MRC score was ≥2 or forced expiratory volume in 1 second was <90% predicted.
Main Results:
- 35% of kidney transplant recipients reported breathlessness.
- 56% of participants required formal respiratory medicine review.
- Underlying respiratory conditions were identified in 33 patients.
Conclusions:
- Respiratory disability and breathlessness are significant issues in kidney transplant recipients.
- Current routine cardiologic evaluations do not address respiratory symptoms comprehensively.
- A pre-transplant pulmonological evaluation including spirometry is recommended for kidney transplant candidates.
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