Recommendations for Donor and Recipient Selection and Risk Prediction: Working Group Report From the ILTS Consensus

Andrea Schlegel1,2, David P Foley3, Eric Savier4

  • 1The Liver Unit, Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham, United Kingdom.

Transplantation
|August 20, 2021
PubMed

Insights

Guidelines for liver transplantation using donation after circulatory death donors (DCDs) were developed. Experts addressed donor and recipient risk factors and prediction models for DCD liver transplants (DCD-LT).

Area of Science:

  • Hepatology
  • Transplantation Surgery
  • Organ Donation

Background:

  • Donation after circulatory death donors (DCDs) are increasingly used for liver transplantation (LT).
  • Current clinical practice lacks universally accepted criteria for DCD donor and recipient risk factors and prediction models.
  • This highlights a need for standardized guidelines in DCD liver transplantation (DCD-LT).

Framework:

  • A consensus conference by the International Liver Transplantation Society convened experts on January 31, 2020, in Venice, Italy.
  • The conference utilized a grade system to review global DCD-LT practices.
  • International experts formed 6 working groups to develop evidence-based recommendations.

Implementation:

  • Working groups addressed specific questions on donor and recipient risk factors and prediction models in DCD-LT.
  • Recommendations were based on a thorough review of existing scientific literature.
  • Conference attendees and working group members acted as a jury to finalize these recommendations.

Implications:

  • The report presents consensus-based statements and guidelines for DCD-LT.
  • These recommendations aim to standardize the use of DCD donors in liver transplantation.
  • The findings will guide clinical practice regarding donor and recipient selection and risk assessment in DCD-LT.

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