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Effects of Forssman antibody on renal function of the guinea pig
J E Barbosa1, W Sarti, G B Mello
1Dept. of Parasitology, Medical School of Ribeirão Preto, Univesity of São Paulo, SP-Brazil.
Research in Experimental Medicine. Zeitschrift Fur Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie
|January 1, 1987
Abstract:
When guinea pigs were injected with rabbit anti-sheep red blood cell antiserum (Forssman antibody) by the intra arterial (i.a.) route (abdominal aorta at the level of the renal arteries), they developed renal disfunction. A diminished glomerular filtration rate associated with a 27% increase in the fractional excretion of K+ was observed. No alterations were noted in the fractional excretion of water and NA+.