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Published on: February 4, 2018
Long-term Outcomes in Treated Lyme Carditis
Chang Nancy Wang1, Cynthia Yeung1, Andres Enriquez1
1Queen's University, Kingston, ON, Canada.
Insights
Long-term outcomes for Lyme carditis (LC) patients treated with antibiotics and stress tests are positive. Most patients recover fully without needing permanent pacemakers, showing stable heart conduction post-treatment.
Area of Science:
- Cardiology
- Infectious Diseases
- Tick-borne Illnesses
Background:
- Lyme carditis (LC) is a common early manifestation of Lyme disease.
- Symptomatic high-degree atrioventricular block (AVB) is the most frequent presentation of LC.
- AVB associated with LC typically resolves with antibiotic treatment.
Purpose of the Study:
- To describe the long-term outcomes of patients diagnosed with Lyme carditis.
- To evaluate the efficacy of a standardized treatment protocol for LC, including antibiotics and pre-discharge stress testing.
Main Methods:
- A retrospective review of 7 patients with serologically confirmed Lyme carditis.
- Patients were treated with a protocol including antibiotics and a pre-discharge stress test to assess atrioventricular node stability.
- Follow-up assessments were conducted to evaluate long-term cardiac conduction and patient activity levels.
Main Results:
- All 7 patients were asymptomatic at a mean follow-up of 20.8 months.
- Patients resumed normal activities and showed no residual conduction abnormalities.
- None of the patients required permanent pacemaker implantation.
Conclusions:
- Lyme carditis, when treated appropriately with antibiotics and monitored for AV node stability, has favorable long-term outcomes.
- Avoidance of permanent pacing is supported in LC patients demonstrating stable conduction at discharge.
- Standardized treatment protocols can lead to full recovery and return to normal activities for LC patients.
Abstract:
Lyme disease is the most reported tick-borne illness in North America. Lyme carditis (LC) is an early-disseminated manifestation of Lyme disease, most commonly presenting as symptomatic high-degree atrioventricular block (AVB) which resolves with appropriate antibiotic therapy. However, long-term outcomes of treated LC have not previously been described. We present a series of 7 patients (median 28 years, 6 male) with serologically confirmed LC treated with a standard protocol developed at our center including antibiotics and pre-discharge stress test to assess AV node stability. At a mean follow-up of 20.8 months, all patients were asymptomatic, had resumed normal activities, and were free of conduction abnormalities. None required permanent pacing. Our study supports avoidance of permanent pacing for LC if conduction is stable at discharge.
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