Large mural thrombus in the distal arch of the aorta without atherosclerotic disease
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Updated: Oct 23, 2025

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography
Published on: May 26, 2015
Mohammed M Uddin1, Mohamad Amer Soudan2, Joseph Sebastian3
1Internal Medicine, Wayne State University, Warren, Michigan, USA mohammed.uddin2@wayne.edu.
Abstract:
Aortic mural thrombus (AMT) is an uncommon cause of arterial thromboembolism. It is very rare in patients without significant cardiovascular risk factors. Many aetiologies can cause AMT, but there are no clear guidelines for the evaluation and treatment. We present the case of a 43-year-old woman without arteriosclerotic disease who was admitted to the hospital with peripheral embolisation from the mural thrombus in the distal arch of the aorta. Therapy with systemic anticoagulation resulted in complete resolution without necessitating any surgical or endovascular interventions. There were no reported recurrence or complications of the intra-aortic thrombus within 1-year surveillance imaging study.
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