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A Cadaveric Study of Dye Spreading: Determining the Ideal Injection Pattern for Masseter Hypertrophy
Peerada Sermswan1, Tanvaa Tansatit2, Jiraroch Meevassana3
1Faculty of Medicine, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand.
Summary
The three-point botulinum toxin injection technique is effective for masseter hypertrophy. Careful injection placement is vital to avoid side effects like asymmetrical smiles or dry mouth.
Area of Science:
- Plastic Surgery
- Anatomy
Background:
- Masseter hypertrophy causes lower facial asymmetry in Asian populations.
- Botulinum toxin injection technique is key for effective treatment.
Purpose of the Study:
- To refine masseter hypertrophy treatment by analyzing botulinum toxin distribution.
- Elucidate injection patterns within the masseter muscle.
Main Methods:
- Thirty masseter muscles were studied using a three-point injection technique.
- Injections of 0.2 or 0.3 mL were administered at Points A, B, or C.
- Muscle dimensions and dye spread were measured to determine distribution.
Main Results:
- Average masseter dimensions: length 69.87mm, width 33.50mm, thickness 11.23mm.
- Average dye spread: longitudinal 36.56mm, horizontal 15.60mm.
- No significant difference in spread between 0.2mL and 0.3mL injections.
Conclusions:
- The three-point technique is recommended for masseter hypertrophy treatment.
- Injections at Points B and C risk affecting the risorius muscle and parotid gland.
- Dosage should be tailored to muscle volume, not solely thickness.

