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Updated: Oct 23, 2025

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors
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GABAA receptors: structure, function, pharmacology, and related disorders

Amr Ghit1,2, Dina Assal3, Ahmed S Al-Shami4,5

  • 1Department of Biology and Biotechnology, University of Pavia, Pavia, Italy. amr.saadshehatariz01@universitadipavia.it.

Journal, Genetic Engineering & Biotechnology
|August 21, 2021
PubMed
Summary

This review summarizes gamma-aminobutyric acid subtype A receptors (GABAARs), their structure, function, and associated CNS disorders. Understanding GABAAR properties is crucial for developing new treatments for neurological diseases.

Keywords:
Allosteric modulationAlzheimer’s diseaseAutism spectrum disorderBarbituratesBenzodiazepineEpilepsyGABAGABAARSchizophrenia

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