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Dermatologic conditions in Down syndrome
Chenin Ryan1, Kishore Vellody2, Leah Belazarian3
1Dartmouth Geisel School of Medicine, Hanover, New Hampshire, USA.
Abstract:
Down syndrome (DS) is the most common chromosomal condition and affects many organs including the skin. Dermatologists are an integral part of the DS care team. This is a review of both common and rare dermatologic conditions in DS. We provide practical strategies for a successful dermatology interview and examination. We explore the downstream effects of trisomy of chromosome 21, in particular on the immune system, and how these insights may enhance our pathophysiologic understanding of their cutaneous conditions.
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