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Updated: Oct 23, 2025
An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium
Published on: December 17, 2018
Effects of cadmium on antioxidant and non-specific immunity of Macrobrachium nipponense
Long Wang1, Jianbin Feng2, Guiling Wang2
1Jiangsu Engineering Laboratory for Breeding of Special Aquatic Organisms, Huaiyin Normal University, Huai'an 223300, China; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture, Shanghai Ocean University, Shanghai 201306, China.
Abstract:
As a non-essential and toxic element, cadmium poses an important threat to aquatic organisms and human food safety. In this study, the effects of cadmium on antioxidant and non-specific immunity of Macrobrachium nipponense were studied from the physiological and biochemical indexes, histology and expression of related genes. These results showed that low concentrations (0.01, 0.02 mg/L) of cadmium have a positive effect on the non-specific immunity of M. nipponense, but high concentration (0.04 mg/L) of cadmium could inhibit or even damage the non-specific immunity of M. nipponense. The cadmium could induce oxidative stress in M. nipponense, and M. nipponense actived the antioxidant defense system to deal with oxidative stress, but high concentration (0.04 mg/L) of cadmium could inhibit the antioxidant defense system of M. nipponense, leading to oxidative damage, and may induce apoptosis in severe case. At the same time, the results of histology showed that cadmium can damage the structure of gill and hepatopancreas tissues of M. nipponense. This study provides theoretical data for evaluating the influences of heavy metal cadmium on M. nipponense and the toxic mechanism of heavy metal cadmium.
