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Related Experiment Video

Updated: Oct 23, 2025

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
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Monitoring medication response in ADHD: what can continuous performance tests tell us?

K Cedergren1, S Östlund1, J Åsberg Johnels1

  • 1Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, Kungsgatan 12A, 411 19, Gothenburg, Sweden.

European Archives of Psychiatry and Clinical Neuroscience
|August 22, 2021
PubMed
Summary

ADHD medication effectively reduces symptoms, as shown by the QbTest and ADHD Rating Scale (ADHD-RS). The QbTest may also help predict medication non-compliance in children and adolescents.

Keywords:
ADHDAdolescentsChildrenContinuous performance testEffectivenessLong-term medication

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Area of Science:

  • Neuroscience
  • Pediatrics
  • Psychopharmacology

Background:

  • Long-term ADHD medication effectiveness and compliance monitoring are crucial.
  • Objective and subjective measures are needed to assess treatment outcomes.

Purpose of the Study:

  • To evaluate the one-year effectiveness of ADHD medication using the QbTest and ADHD Rating Scale (ADHD-RS).
  • To explore the QbTest's potential in predicting medication compliance.

Main Methods:

  • A one-year longitudinal study involving 78 children (6-18 years) with ADHD.
  • Utilized the QbTest (continuous performance test with motion tracking) and ADHD-RS at baseline, 1 month, and 12 months.
  • Analyzed symptom changes and correlations between measures, including dropout analysis.

Main Results:

  • Significant reductions in ADHD symptoms were observed on both QbTest and ADHD-RS from baseline to 1 and 12 months.
  • A weak but significant correlation was found between QbTest and ADHD-RS changes from baseline to 1 month.
  • Children who dropped out showed less severe inattention symptoms at baseline on the QbTest.

Conclusions:

  • Both QbTest and ADHD-RS demonstrate robust ADHD symptom improvement with medication over one year.
  • The QbTest shows potential as a tool for monitoring medication effects and predicting non-compliance.
  • Further research is needed for reliable long-term medication and compliance monitoring.