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[Zinc and its status in some dermatologic diseases--a statistical assessment]
Zeitschrift Fur Hautkrankheiten
|January 1, 1987
Summary
This study found significant differences in zinc, magnesium, and copper levels in patients with various skin conditions. Notably, vitiligo patients had low zinc, while psoriasis patients showed high zinc levels.
Area of Science:
- Dermatology and Nutritional Biochemistry
Context:
- Investigates the relationship between dermatological conditions and essential mineral levels.
- Analyzes blood and serum concentrations of zinc, magnesium, and copper in patients with various skin diseases.
Purpose:
- To statistically interpret blood and serum mineral levels in patients with alopecia areata, alopecia androgenetica, psoriasis vulgaris, vitiligo, rosacea, venous ulcer, and atopic eczema.
- To compare these levels with those of healthy individuals.
Summary:
- Significant low blood-zinc levels were observed in vitiligo patients.
- Elevated blood-zinc levels were found in all psoriasis vulgaris patients.
- Low serum-zinc and blood-copper levels were noted across multiple diagnoses.
- Blood and serum magnesium levels were similar across dermatological diseases, showing an overall increase compared to controls (p=0.05).
- Linear dependencies were identified between mineral levels and specific diseases.
- A normal distribution for magnesium levels, as often cited, was not confirmed.
Impact:
- Highlights potential diagnostic or therapeutic roles of zinc, magnesium, and copper in specific dermatological conditions.
- Suggests altered mineral metabolism in various skin diseases.
- Challenges existing literature regarding magnesium level distribution in these patient groups.