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[Anatomic principles for digestion and immune function in the gastrointestinal tract]
1Topographische Anatomie und Biomechanik, Zentrum Anatomie, MH Hannover.
All the cells necessary for the afferent and efferent branch of the immune reaction are present in the intestinal wall. There is a continuous migratory flow of lymphatic cells (MALT = mucosa-associated lymphatic tissue). Experiments in oral immunisation have also recently provided data for clinical use of these migratory paths of IgA precursor cells. The mast cells in the mucosa show heterogeneity and can be differentiated not only by size, life span and origin, but also by the number of granules and the content of mediators. For further research on the cells in the immune system in the wall of the digestive tract new cell markers and functional tests are necessary.
All the cells necessary for the afferent and efferent branch of the immune reaction are present in the intestinal wall. There is a continuous migratory flow of lymphatic cells (MALT = mucosa-associated lymphatic tissue). Experiments in oral immunisation have also recently provided data for clinical use of these migratory paths of IgA precursor cells. The mast cells in the mucosa show heterogeneity and can be differentiated not only by size, life span and origin, but also by the number of granules and the content of mediators. For further research on the cells in the immune system in the wall of the digestive tract new cell markers and functional tests are necessary.