Related Experiment Video

Updated: Aug 9, 2026

Intracranial Injection of Adeno-associated Viral Vectors
08:47

Intracranial Injection of Adeno-associated Viral Vectors

Published on: November 17, 2010

48.1K

Temporal Association Between the COVID-19 Ad26.COV2.S Vaccine and Acute Myocarditis: A Case Report and Literature

Imran Sulemankhil1, Mohammad Abdelrahman2, Smita I Negi2

  • 1Department of Internal Medicine, The Jewish Hospital, 4777 East Galbraith Rd, Cincinnati, OH 45236, United States of America.

Cardiovascular Revascularization Medicine : Including Molecular Interventions
|August 23, 2021
PubMed

Insights

The Janssen vaccine may be associated with myocarditis, a rare side effect. However, COVID-19 vaccines significantly reduce severe illness, and their benefits outweigh potential risks.

Area of Science:

  • Immunology
  • Cardiology
  • Public Health

Background:

  • Widespread vaccination against Coronavirus Disease 2019 (COVID-19) has decreased severe infections.
  • While vaccines are effective, rare serious side effects have been reported.
  • This review focuses on myocarditis, a potential adverse event.

Observation:

  • A case of myocarditis following the Janssen vaccine in a young male is presented.
  • A literature review on COVID-19 vaccine-related myocarditis and its pathogenesis was conducted.
  • A temporal association between vaccination and myocarditis was noted.

Findings:

  • Myocarditis is a rare but reported side effect of COVID-19 vaccines.
  • The pathogenesis of vaccine-related myocarditis is still under investigation.
  • A case of myocarditis after Janssen vaccination is detailed.

Implications:

  • Healthcare providers should be aware of the potential for myocarditis post-vaccination.
  • Continued monitoring and research into vaccine side effects are crucial.
  • The benefits of COVID-19 vaccination in preventing severe disease significantly outweigh the risks.

Keywords:
COVID-19MyocarditisVaccine

More Related Videos

Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model07:35

Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model

Published on: December 10, 2021

2.1K
Simultaneous 3D Analysis of Cardiac Damage and Immune Response in Reperfused Acute Myocardial Infarction Using Light Sheet Fluorescence Microscopy06:38

Simultaneous 3D Analysis of Cardiac Damage and Immune Response in Reperfused Acute Myocardial Infarction Using Light Sheet Fluorescence Microscopy

Published on: September 26, 2025

497

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...