Related Experiment Video
Updated: Oct 23, 2025
09:36
Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
27.4K
Caution, "normal" BMI: health risks associated with potentially masked individual underweight-EPMA Position Paper
Olga Golubnitschaja1, Alena Liskova2, Lenka Koklesova2
1Predictive, Preventive and Personalised (3P) Medicine, Department of Radiation Oncology, University Hospital Bonn, Rheinische Friedrich-Wilhelms-Universität Bonn, 53127 Bonn, Germany.
The EPMA Journal
|August 23, 2021
Summary
Optimal body weight varies individually, not just by standard metrics. Personalized medicine, considering genetics and lifestyle, is key for preventing diseases and improving health outcomes across many medical fields.
Area of Science:
- Personalized Medicine
- Preventive Healthcare
- Health Risk Assessment
Background:
- Standardized "normal" body weight may not be optimal for all individuals.
- Individual factors like genetics, origin, and lifestyle significantly influence optimal weight.
- Overweight and underweight are risk factors for metabolic shifts and severe pathologies.
Purpose of the Study:
- To advocate for personalized medicine principles in determining optimal body weight.
- To highlight the need for innovative screening programs for population health.
- To emphasize tailored prevention and treatment strategies based on individual profiles.
Main Methods:
- Applying the "one size does not fit all" principle of personalized medicine.
- Developing comprehensive individual patient profiles.
- Utilizing multi-parametric analysis for health risk assessment.
Main Results:
- Identifying optimal weight requires considering genetic predisposition, geographic origin, and lifestyle.
- Personalized screening and profiling can lead to cost-effective, targeted prevention.
- Predictive, Preventive, and Personalised Medicine (PPPM/3PM) offers long-term healthcare economy benefits.
Conclusions:
- A paradigm shift from reactive to PPPM/3PM is essential for improved healthcare.
- Collaboration among stakeholders is crucial for implementing PPPM/3PM.
- Personalized approaches benefit numerous healthcare areas, from metabolic disorders to pandemic preparedness.
Keywords:
AdultsAnorexia athleticaAnthropometricsArtificial intelligence in medicineBMI deviationBig data managementBiomarker panelBody fluidsBody weightCOVID-19CancersCardiovascular diseaseCommunicableDeficitsDisease developmentElderlyEndothelin-1FatFlammer syndromeHealth economyHealth policyHealthcareHypoxic effectsImmune systemIndividualised patient profileInflammationInnovative population Screening ProgrammeIntentionalManifestationMedical imagingMetabolic pathwaysMicrobiomeModellingMolecular patternsMulti-level diagnosticsMulti-parametric analysisNeurodegenerationNeurologyNon-communicable disordersNutritionOverweightPathologyPopulation healthPredictive preventive personalised medicine (3PM/PPPM)PregnancyProgressionROSReproductive dysfunctionSports medicineStrokeSystemic ischemiaUnderweightUnintentionalVasoconstrictionWeight lossWell-beingWound healingYouthMore Related Videos
03:35Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
Published on: December 1, 2023
413
06:48Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research
Published on: June 7, 2024
1.6K
Related Concept Videos
01:24Obesity
772
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
772
01:21Drug Dosing: Obese Patients
30
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
30
01:26Stress Prevention and Stress Management Techniques IV
86
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
86
01:28Anorexia Nervosa
305
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
305
01:25Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
40
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
40
01:30Bulimia Nervosa
279
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
279