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Updated: Oct 23, 2025
X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
Published on: May 13, 2020
Crystal structures of two polymorphs of tixocortol pivalate
Yoann Rousselin1, Sylvie Yolka2, Alexandre Clavel2
1ICMUB - UMR 6302, Université Bourgogne Franche Comte, 9 avenue Alain Savary, 21000 DIJON, France.
Abstract:
Two polymorphs, (I) and (II), of (S)-{2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihy-droxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-deca-hydro-1H-cyclo-penta-[a]phenanthren-17-yl]-2-oxoeth-yl} 2,2-di-methyl-propane-thio-ate, C26H38O5S, have been identified. They are ortho-rhom-bic, non-centrosymmetric (P212121). The structures display layers of mol-ecules conected via O-H⋯O hydrogen bonds along the b-axis direction in polymorph (I) and along the c-axis direction in polymorph (II). The structure of (II) exhibits disorder of the main mol-ecule.
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