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Updated: Oct 23, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Antibiotic overuse after discharge from medical short-stay units
Nathaniel S Soper1, Abhinav J Appukutty2, David Paje1
1Division of Hospital Medicine, Department of Internal Medicine, Michigan Medicine, Ann Arbor, Michigan.
Abstract:
Of 100 patients discharged from short-stay units (SSUs) with antibiotics, 47 had a skin and soft-tissue infection, 22 had pneumonia, and 21 had a urinary tract infection. Among all discharge antibiotic prescriptions, 78% involved antibiotic overuse, most commonly excess duration (54 of 100) and guideline discordant selection (44 of 100).
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