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Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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Drugging the undruggable proteins in cancer: A systems biology approach

Shivanthy Pathmanathan1, Ingrid Grozavu2, Anna Lyakisheva2

  • 1Donnelly Centre, University of Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Ontario, Canada.

Current Opinion in Chemical Biology
|August 24, 2021
PubMed

Keywords:
Cancer researchDifficult-to-drug proteomeDrug discoveryE3 ligases and deubiquitinasesHigh-throughputMYCOmicsPrecision medicineRASSystems BiologyTP53Undruggable oncogenes

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