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Evolutionary warning system for COVID-19 severity: Colony predation algorithm enhanced extreme learning machine
Beibei Shi1, Hua Ye2, Long Zheng2
1Affiliated People's Hospital of Jiangsu University, 8 Dianli Road, Zhenjiang, Jiangsu, 212000, China.
Insights
This study introduces an AI model using biochemical indicators for accurate COVID-19 diagnosis and severity classification. The ECPA-KELM model demonstrates improved predictive performance and stability for early disease detection and treatment.
Area of Science:
- Biomedical Informatics
- Artificial Intelligence in Healthcare
- Computational Biology
Background:
- The global spread of COVID-19 (Coronavirus Disease 2019) caused by SARS-CoV-2 has highlighted critical needs for early diagnosis and effective severity assessment.
- Current diagnostic and clinical care approaches for COVID-19 face limitations, leading to high mortality rates.
Purpose of the Study:
- To investigate the utility of biochemical indicators for discriminating and classifying COVID-19 severity using machine learning.
- To develop an efficient artificial intelligence method for COVID-19 diagnosis based on biochemical data.
Main Methods:
- A novel framework, ECPA-KELM, was developed by integrating an enhanced colony predation algorithm (ECPA) with a kernel extreme learning machine (KELM).
- The ECPA algorithm incorporates operators from grey wolf and moth-flame optimizers to enhance parameter optimization and feature selection for KELM.
- The ECPA algorithm's performance was validated using the IEEE CEC2017 benchmark dataset.
Main Results:
- The ECPA-KELM model demonstrated superior predictive properties and enhanced stability compared to other KELM models in diagnosing COVID-19 using biochemical indexes.
- Statistical analysis confirmed the improved performance metrics of the proposed ECPA-KELM model.
Conclusions:
- The ECPA-KELM model shows significant potential as a computer-aided diagnostic tool for COVID-19.
- This approach can effectively discriminate and classify COVID-19 severity, offering an early warning system for timely treatment and diagnosis.
Abstract:
Coronavirus Disease 2019 (COVID-19) was distributed globally at the end of December 2019 due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Early diagnosis and successful COVID-19 assessment are missing, clinical care is ineffective, and deaths are high. In this study, we investigate whether the level of biochemical indicators helps to discriminate and classify the severity of the COVID-19 using the machine learning method. This research creates an efficient intelligence method for the diagnosis of COVID-19 from the perspective of biochemical indexes. The framework is proposed by integrating an enhanced new stochastic called the colony predation algorithm (CPA) with a kernel extreme learning machine (KELM), abbreviated as ECPA-KELM. The core feature of the approach is the ECPA algorithm which incorporates the two main operators that have been abstained from the grey wolf optimizer and moth-flame optimizer to improve and restore the CPA research functions and are simultaneously used to optimize the parameters and to select features for KELM. The ECPA output is checked thoroughly using IEEE CEC2017 benchmark to verify the capacity of the proposed methodology. Finally, in the diagnosis of COVID-19 using biochemical indexes, the designed ECPA-KELM model and other competing KELM models based on other optimization are used. Checking statistical results will display improved predictive properties for all metrics and higher stability. ECPA-KELM can also be used to discriminate and classify the severity of the COVID-19 as a possible computer-aided method and provide effective early warning for the treatment and diagnosis of COVID-19.
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