An Eggshell-Based Toothpaste as a Cost-Effective Treatment of Dentin Hypersensitivity

Area of Science:

• Biomaterials Science
• Dental Research
• Nanotechnology

Background:

• Dentin hypersensitivity is a common dental condition.
• Effective occlusion of dentinal tubules is crucial for managing dentin hypersensitivity.
• Natural ingredient-based toothpastes offer potential alternatives to conventional treatments.

Purpose of the Study:

• To evaluate the efficacy of two novel eggshell-based toothpastes in occluding dentinal tubules.
• To compare the performance of eggshell toothpaste (ESTP) and TNPs-containing eggshell toothpaste (TNPsESTP) against a positive control.

Main Methods:

• Two experimental toothpastes (ESTP and TNPsESTP) were formulated using natural ingredients.
• Human dentin discs were artificially etched to simulate hypersensitivity.
• Treated dentin samples were analyzed using cross-polarization optical coherence tomography (CP-OCT) and scanning electron microscopy (SEM) after 2 weeks and 1 month.

Main Results:

• Both ESTP and TNPsESTP demonstrated increased dentin surface reflectivity and density compared to the positive control.
• ESTP showed comparable complete occlusion of dentinal tubules to the positive control at 2 weeks.
• Both toothpastes significantly increased partially occluded dentinal tubules at 1 month.

Conclusions:

• EstP and TNPsESTP are effective in occluding dentinal tubules.
• These eggshell-based toothpastes represent a cost-effective approach for managing dentin hypersensitivity.
• Further research may explore long-term efficacy and clinical applications.