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Reinke's oedema and thyroid function: a prospective study in 43 patients
H Lindeberg1, J U Felding, H Søgaard
1Department of Otorhinolaryngology, University Hospital, Aarhus, Denmark.
Clinical Otolaryngology and Allied Sciences
|December 1, 1987
Summary
This study investigated thyroid function in patients with Reinke's edema. While some hypothyroidism was detected, most patients did not show thyroid hypofunction, and vocal cord staining did not correlate with thyroid status.
Area of Science:
- Otolaryngology
- Endocrinology
Background:
- Reinke's edema is a laryngeal condition affecting the vocal cords.
- Thyroid dysfunction is sometimes associated with laryngeal changes.
Purpose of the Study:
- To analyze thyroid function in patients diagnosed with Reinke's edema.
- To explore potential correlations between vocal cord biopsy staining and thyroid parameters.
Main Methods:
- Thyroid function tests were performed on 43 patients with Reinke's edema.
- Alcian-blue staining intensity of vocal cord biopsies was assessed.
- Thyroid parameters were compared with staining results.
Main Results:
- Two new cases of myxedema and two borderline cases were identified among the 43 patients.
- The majority of patients with Reinke's edema did not exhibit thyroid hypofunction.
- No significant relationship was found between alcian-blue staining intensity and thyroid parameters.
Conclusions:
- Thyroid hypofunction is not a universal finding in patients with Reinke's edema.
- Vocal cord biopsy staining characteristics do not appear to be linked to thyroid function in this patient group.