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Related Experiment Video

Updated: Oct 23, 2025

Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms

Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms

Published on: May 29, 2020

Drug-Induced Liver Injury After COVID-19 Vaccine.

Rupinder Mann¹, Sommer Sekhon², Sandeep Sekhon³

¹Internal Medicine, Saint Agnes Medical Center, Fresno, USA.

|August 25, 2021

Summary

COVID-19 vaccines are safe, but rare cases of liver injury have been reported. This case study details a patient experiencing liver injury following COVID-19 vaccination.

Keywords:

covid-19 covid-19 pandemic covid-19 vaccine drug-induced liver injury liver dysfunctions

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Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms

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Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube

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Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro

Published on: January 31, 2022

Area of Science:

Hepatology
Vaccinology
Infectious Diseases

Background:

The COVID-19 pandemic, caused by SARS-CoV-2, has led to widespread morbidity and mortality.
Numerous vaccines have been developed and approved, demonstrating high safety and efficacy.
Drug-induced liver injury (DILI) is a known concern, though rare with vaccines.

Observation:

A case of liver injury following COVID-19 vaccination is presented.
The patient developed symptoms indicative of hepatic distress post-vaccination.
Diagnostic workup confirmed liver injury potentially linked to the vaccine.

Findings:

The presented case highlights a rare instance of hepatotoxicity after COVID-19 vaccination.
While vaccines have excellent safety profiles, monitoring for adverse events remains crucial.
This case contributes to the understanding of potential vaccine-related side effects.

Implications:

Further investigation into rare vaccine-associated liver injury is warranted.
Clinicians should be aware of potential hepatotoxicity in patients presenting with liver issues post-vaccination.
Continued pharmacovigilance is essential for ensuring vaccine safety and public trust.