An Unusual Presentation of Extra-Oral Plasmablastic Lymphoma With Unique Cytomorphology

Plasmablastic lymphomas are high-grade lymphomas most commonly observed in the oral cavity. Their association with HIV-infected patients is now well-known. The occurrence of plasmablastic lymphomas in extra-oral sites in immunocompetent patients is exceedingly rare. We aim to document such a rare case in a 69-year- old female in the gastrointestinal tract along with lymphomatous effusion of the pleural cavity. The discussed case also needs a mention for its unique cytomorphological features. The diagnosis was confirmed by immunohistochemical stains, which play a vital role in the accurate diagnosis of plasmablastic lymphomas and their distinction from other anaplastic non-Hodgkin lymphomas.