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Evolution of Mortality by Age Group in Patients With COVID-19 Above 60 Years of Age

Maria Regina Pereira de Godoy1, Maria Lucia Machaso Salomão2, Flavia Queiroz3

  • 1Clinica Medica, Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto, BRA.

Cureus
|August 25, 2021
PubMed

Insights

Older adults experienced higher COVID-19 mortality, though vaccination reduced hospitalizations. Further research is needed to understand vaccine protection against mortality in this vulnerable group.

Area of Science:

  • Medicine
  • Epidemiology
  • Public Health

Background:

  • Coronavirus disease 2019 (COVID-19) poses a significant threat, particularly to older populations.
  • Disease severity and mortality rates are heightened in elderly COVID-19 patients.

Purpose of the Study:

  • To analyze COVID-19 hospitalizations and mortality trends in patients over 60 years old.
  • To assess age-specific mortality patterns in older adults during the pandemic.

Main Methods:

  • Retrospective clinical trial analysis of 2,359 patients over 60 admitted to a Brazilian reference center.
  • Data collected from March 2020 to April 2021, with mortality analyzed across 10-year age groups.
  • Fisher's exact test used to evaluate increases in age-specific mortality.

Main Results:

  • An increasing trend in mortality was observed across decades within the study period.
  • A notable reduction in hospitalizations was documented following patient vaccination.
  • Vaccination demonstrated a positive impact on reducing hospital admissions for older adults.

Conclusions:

  • Mortality rates for COVID-19 are significantly higher in patients over 60 compared to younger individuals.
  • While vaccines have decreased hospitalization rates in this demographic, their impact on mortality requires additional investigation.
  • Further evaluation is necessary to fully ascertain the protective effect of vaccines against COVID-19 mortality in the elderly.

Keywords:
covid-19hospitalizationmortalityoldpeople

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