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Updated: Oct 23, 2025

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
Published on: May 8, 2018
Real-time respiratory motion compensated roadmaps for hepatic arterial interventions
Martin G Wagner1, Sarvesh Periyasamy2, Colin Longhurst3
1Department of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, USA.
This study developed a respiratory motion compensated guidance system for hepatic arterial interventions. The system significantly improved guidewire accuracy by accounting for liver movement during procedures.
Area of Science:
- Medical Imaging
- Interventional Radiology
- Biomedical Engineering
Background:
- Hepatic arterial interventions rely on static roadmap overlays for catheter navigation.
- Respiratory motion causes discrepancies between the roadmap and actual anatomy, complicating procedures.
Purpose of the Study:
- To develop and evaluate a dynamic respiratory motion compensated device guidance system.
- To improve accuracy and real-time performance in hepatic arterial interventions.
Main Methods:
- A respiratory motion model of the hepatic vasculature was created from X-ray sequences.
- Deep learning segmented guidewires and catheters from live fluoroscopic images.
- Real-time compensated displays (vessel or device) were evaluated in a porcine model.
Main Results:
- The motion compensated system achieved a median error of 1.08 mm.
- Guidewire tip accuracy in the correct vessel branch was significantly higher (86% vs. 69%) with compensated displays.
- Average processing time was 17 ms per frame.
Conclusions:
- The developed system enhances the accuracy of device positioning relative to hepatic vasculature.
- The integrated display modes simplify physician workflow by combining vessel and device information.
- Processing times are clinically feasible for real-time application.
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