Related Experiment Video
Updated: Oct 23, 2025

Humanized Mouse Model to Study Bacterial Infections Targeting the Microvasculature
Published on: April 1, 2014
Cutaneous small vessel vasculitis triggered by Fusobacterium infection
R Nancarrow-Lei1, D Drodge1, C Gollins1
1Department of Dermatology, Southmead Hospital, North Bristol NHS Trust, Bristol, UK.
A rare case of cutaneous small vessel vasculitis in a 94-year-old woman is presented. Researchers hypothesize Fusobacterium necrophorum infection as the potential trigger for this condition.
Area of Science:
- Dermatology
- Infectious Diseases
- Rheumatology
Background:
- Cutaneous small vessel vasculitis (cSVS) is an inflammatory condition affecting superficial blood vessels.
- cSVS can manifest with diverse clinical presentations, posing diagnostic challenges.
Observation:
- A 94-year-old female patient presented with clinical signs suggestive of cSVS.
- The patient's medical history and clinical examination were meticulously documented.
Findings:
- The clinical presentation was consistent with cutaneous small vessel vasculitis.
- A hypothesis was formulated suggesting Fusobacterium necrophorum as the causative agent.
Implications:
- This case highlights the potential role of Fusobacterium necrophorum in triggering vasculitic syndromes.
- Further research may elucidate the pathogenic mechanisms linking this bacterium to vasculitis.
- Understanding such associations can improve diagnostic and therapeutic strategies for vasculitis.
More Related Videos
07:14A CFSE-based Assay to Study the Migration of Murine Skin Dendritic Cells into Draining Lymph Nodes During Infection with Mycobacterium bovis Bacille Calmette-Guérin
Published on: October 9, 2016
10:45Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Inflammatory Response I: Vascular and Cellular