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Impaired glucose tolerance in pulmonary tuberculosis
1Atatürk Chest Diseases and Thoracic Surgery Centre, Department of Pulmonary Medicine, Ankara, Turkey.
European Journal of Respiratory Diseases
|November 1, 1987
Summary
Impaired glucose tolerance (IGT) is more common in active pulmonary tuberculosis. This glucose intolerance often resolves with chemotherapy, indicating a link to the active disease phase.
Area of Science:
- Endocrinology
- Infectious Diseases
- Pulmonology
Background:
- Pulmonary tuberculosis (TB) is a significant global health concern.
- Metabolic disturbances, including glucose metabolism, can be affected by infectious diseases.
Purpose of the Study:
- To investigate the prevalence of impaired glucose tolerance (IGT) in patients with active pulmonary tuberculosis.
- To assess if IGT in TB patients is reversible with treatment.
Main Methods:
- Glucose tolerance tests were conducted on 80 participants: 30 with active pulmonary TB, 24 with nonspecific pulmonary infection, and 26 healthy controls.
- New diagnostic criteria were applied to identify IGT.
Main Results:
- Impaired glucose tolerance was diagnosed in 4 TB patients and 3 patients with nonspecific pulmonary infection.
- No IGT was observed in the control group.
- Three TB patients showed normalized glucose tolerance after 2 months of chemotherapy.
Conclusions:
- Active pulmonary tuberculosis is associated with a higher incidence of impaired glucose tolerance.
- The observed IGT in TB patients appears to be transient and linked to the active phase of the disease, resolving with effective treatment.