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Updated: Oct 23, 2025

Simple, Affordable, and Modular Patterning of Cells using DNA
Published on: February 24, 2021
Digital Numbers Constructed by Fine Patterned Polydopamine on DNA Templates
Meizhou Zhang1, Shuangshuang Wang1, Longjie Li1,2
1Hubei Key Laboratory of Bioinorganic Chemistry and Materia Medica, Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, Hongshan, Wuhan, 430074, P. R. China.
Abstract:
Using DNA nanostructures as templates to synthesize shape-controlled polydopamine (PDA) is a promising strategy to realize the fabrication of exquisite PDA nanomaterials. However, previous studies using small DNA tiles as templates could only afford very simple structures such as lines and crosses due to the limited space on the template and the relatively low resolution of the PDA nanopatterns. Therefore, the best resolution of the PDA nanostructures that can be achieved by this technique is carefully investigated. And by connecting several DNA tiles together, larger DNA templates are built up and achieve the synthesis of complicated digital nanopatterned PDA structures.
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