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Intramuscular injection safety without aspiration in the ventro-gluteal region during vaccination: randomized
Alanna Michella Oliveira de Albuquerque da Silva1, Regina Célia Sales Santos1, Maria Gabriella Silva Araujo1
1Universidade Federal de Alagoas. Maceió, Alagoas, Brazil.
Objectives:
to compare adverse events after administrating hepatitis A vaccine intramuscularly in the ventro-gluteal region between techniques with and without aspiration.
Methods:
randomized double-blind clinical trial, using hepatitis A vaccine (inactivated) in the ventro-gluteal region, with a sample of 74 participants in the intervention group, vaccinated with the slow injection technique without aspiration, and 74 participants in the control group undergoing slow injection with aspiration. Daily assessment of participants was carried out in the 72 hours after vaccination, in order to ascertain local, systemic adverse events, local and contralateral temperatures.
Results:
the occurrence of local and systemic adverse events was homogeneous between the groups in the three days after vaccination (p>0.05). There was no influence of sex, race, pre-existing disease and use of medication.
Conclusions:
the intramuscular vaccination technique without aspiration in the ventro-gluteal region is safe for adverse events following immunization compared to the conventional technique with aspiration.
