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Updated: Oct 23, 2025

Advanced Glycation End-Products Sensitize Human Sensory-Like Neuron Cells to Capsaicin-Induced Calcium Influx
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Advanced Glycation End-Products Sensitize Human Sensory-Like Neuron Cells to Capsaicin-Induced Calcium Influx

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Depolarization induces nociceptor sensitization by CaV1.2-mediated PKA-II activation

Jörg Isensee1, Marianne van Cann1, Patrick Despang2

  • 1Department of Anesthesiology and Intensive Care Medicine, Translational Pain Research, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.

The Journal of Cell Biology
|August 25, 2021
PubMed

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