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[Anticoagulation in intensive care medicine]
Patrick Möhnle1, Mathias Bruegel2, Michael Spannagl3
1Abteilung für Transfusionsmedizin, Zelltherapeutika und Hämostaseologie, Klinik für Anästhesiologie, LMU Klinikum München, Ziemssenstr. 1, 80336, München, Deutschland. Patrick.Moehnle@med.uni-muenchen.de.
Medizinische Klinik, Intensivmedizin Und Notfallmedizin
|August 25, 2021
Summary
Critically ill patients face bleeding and clotting risks. This review covers anticoagulation, anti-platelet therapy, and monitoring for intensive care patients, including those with extracorporeal devices.
Area of Science:
- Critical care medicine
- Hematology
- Pharmacology
Background:
- Critically ill patients are prone to hemostasis disorders, increasing risks of bleeding and thromboembolism.
- Management of acute vascular events requires specific anticoagulation or anti-platelet therapy.
- Continuation of anticoagulation in patients with pre-existing conditions during intensive care is crucial.
Purpose of the Study:
- To provide an overview of current aspects of hemostasis disorders in critically ill patients.
- To discuss anticoagulation and anti-platelet therapies in intensive care settings.
- To address challenges related to extracorporeal devices and infection-triggered coagulation disorders.
Main Methods:
- Literature review of current aspects of hemostasis disorders in critically ill patients.
- Discussion of new anticoagulation and anti-platelet drugs.
- Emphasis on laboratory monitoring of anticoagulation.
Main Results:
- New anticoagulation and anti-platelet drugs are available.
- Laboratory monitoring is central to anticoagulation management.
- Specific considerations exist for extracorporeal devices and sepsis-induced coagulopathy.
Conclusions:
- Effective management of hemostasis disorders in critically ill patients is essential.
- Appropriate use of anticoagulation and anti-platelet agents is key.
- Ongoing research and monitoring are vital for optimizing patient outcomes.
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