Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Effects of Radiation02:59

Biological Effects of Radiation

16.3K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
16.3K
Isotopes and Radioisotopes01:28

Isotopes and Radioisotopes

10.4K
In the early 1900s, English chemist Frederick Soddy realized that an element could have atoms with different masses that were chemically indistinguishable. These different types are called isotopes — atoms of the same element that differ in mass. Isotopes differ in mass because they have different numbers of neutrons but are chemically identical because they have the same number of protons. Soddy was awarded the Nobel Prize in Chemistry in 1921 for this discovery.
An isotope containing...
10.4K
Absorption of Radiation01:05

Absorption of Radiation

927
The rate of heat transfer by emitted radiation is described by the Stefan-Boltzmann law of radiation:
927
Radiation: Applications01:17

Radiation: Applications

1.3K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
1.3K
Mutations01:35

Mutations

41.5K
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
41.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Developing Topics.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Design and manufacture of a radioactive 3D printed phantom for PET quality control.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2025
Same author

Establishing measurement traceability for quantitative SPECT imaging.

EJNMMI physics·2025
Same author

Rethinking Dosimetry: A European Perspective.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2025
Same author

A validation protocol for<sup>177</sup>Lu-SPECT image quantification as a basis for multi-centre kidney dosimetry.

Physics in medicine and biology·2025
Same author

Dosimetry Software for Theranostic Applications: Current Capabilities and Future Prospects.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2025

Related Experiment Video

Updated: Oct 23, 2025

Irradiator Commissioning and Dosimetry for Assessment of LQ &#945; and &#946; Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.4K

The internal dosimetry user group position statement on molecular radiotherapy.

Jonathan Gear1,2, Daniel McGowan1,3, Bruno Rojas1,2

  • 1The Internal Dosimetry User Group, England, United Kingdom.

The British Journal of Radiology
|August 25, 2021
PubMed
Summary

The Internal Dosimetry User Group (IDUG) highlights that current molecular radiotherapy practices in the UK often fail to meet Ionising Radiation (Medical Exposure) Regulations 2017 (IR(ME)R) requirements. IDUG proposes ten actions to improve compliance and patient care.

More Related Videos

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities
06:51

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Published on: February 20, 2021

5.2K
A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
09:49

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

10.2K

Related Experiment Videos

Last Updated: Oct 23, 2025

Irradiator Commissioning and Dosimetry for Assessment of LQ &#945; and &#946; Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.4K
Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities
06:51

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Published on: February 20, 2021

5.2K
A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
09:49

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

10.2K

Area of Science:

  • Medical Physics
  • Nuclear Medicine
  • Radiotherapy

Background:

  • The Internal Dosimetry User Group (IDUG) promotes dosimetry in molecular radiotherapy.
  • The Ionising Radiation (Medical Exposure) Regulations 2017 (IR(ME)R) mandate dose optimisation and verification for molecular radiotherapy.
  • Current UK molecular radiotherapy practices frequently do not meet IR(ME)R requirements.

Purpose of the Study:

  • To address the gap in IR(ME)R compliance for molecular radiotherapy in the UK.
  • To propose actionable steps for stakeholders to ensure regulatory adherence.
  • To support the advancement of molecular radiotherapy through improved dosimetry practices.

Main Methods:

  • The study identifies non-compliance with IR(ME)R in current UK molecular radiotherapy treatments.
  • IDUG has developed ten specific points of action for legislative implementation.
  • The group urges stakeholder support for these proposals.

Main Results:

  • Many molecular radiotherapy treatments in the UK are not fully compliant with IR(ME)R.
  • There is a risk of further deviation from compliance, potentially leading to suboptimal patient therapies.
  • IDUG's ten proposed actions aim to facilitate successful implementation of the legislation.

Conclusions:

  • Urgent action is needed to align UK molecular radiotherapy with IR(ME)R standards.
  • National provision must be enhanced to meet compliance criteria.
  • Implementing IDUG's proposals is crucial for patient well-being and the future of molecular radiotherapy.