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Related Concept Videos

Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

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Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
253
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

94
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
94
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

121
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
121
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

97
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
97
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

97
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
97
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

131
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
131

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Related Experiment Video

Updated: Oct 22, 2025

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
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Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding

Published on: August 30, 2024

932

Carcinoid Right Heart Disease.

Alejandro Sanchez-Nadales1, Valentina Celis-Barreto2, Andrea Anampa-Guzman3

  • 1Department of Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL, USA.

Journal of Medical Cases
|August 26, 2021
PubMed
Summary
This summary is machine-generated.

Carcinoid heart disease, a rare cause of right heart failure, was effectively treated with valve surgery in a metastatic carcinoid tumor patient. This intervention improved ventricular dysfunction, highlighting surgery as the definitive treatment.

Keywords:
Carcinoid heart diseaseEchocardiographyPulmonary valve replacementRight-sided heart failureTricuspid valve replacement

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Area of Science:

  • Cardiology
  • Oncology

Background:

  • Carcinoid heart disease (CHD) is an uncommon cause of right-sided heart failure.
  • Metastatic carcinoid tumors, particularly from the appendix, can lead to CHD.

Observation:

  • A 53-year-old male with metastatic appendiceal carcinoid tumors presented with severe right-sided valvular disease, right ventricle dilation, and pulmonary hypertension.
  • The patient's carcinoid syndrome was managed with lanreotide, but cardiac symptoms persisted.

Findings:

  • The patient underwent successful tricuspid and pulmonary valve replacement, along with a maze procedure and right ventricular outflow tract reconstruction.
  • Post-surgery, significant improvement in ventricular dysfunction was observed, confirming CHD as the cause of pure right heart failure.

Implications:

  • Valve surgery is the definitive treatment for carcinoid heart disease in suitable patients.
  • Early diagnosis and surgical intervention are crucial for managing CHD and improving patient outcomes.
  • Carcinoid heart disease necessitates a high index of suspicion in patients with carcinoid syndrome.