Evolving Challenges in Diagnosis of Renal Vasculitis

Renal-limited vasculitis is a rare anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis that presents only with a renal manifestation in the absence of other organs involvement. In this report, a 50-year-old female presented with nonspecific symptoms and anemia, who was subsequently discovered to have renal-limited vasculitis. After receiving a combination of steroid and immunosuppressive therapy, she recovered uneventfully without further relapse. A wide range of nonspecific presenting symptoms and the insidious nature of renal disease often delay in early recognition of renal-limited vasculitis. Keeping a lower threshold of initiating vasculitis workup helps detect the earlier diagnosis which is crucial in management with improved renal outcome.