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Updated: Oct 22, 2025

Extracellularly Identifying Motor Neurons for a Muscle Motor Pool in Aplysia californica
Published on: March 25, 2013
Electrophysiologic Mapping of the Extraocular Motor Nuclei
Justin W Silverstein1,2, Jason A Ellis3
1Neurology, Lenox Hill Hospital Northwell Health, New York, USA.
Abstract:
Mapping the floor of the fourth ventricle to identify the motonuclei of cranial nerves VII-XII has been well-described. Though there are some reports of stimulating the pontomesencephalic surface to identify the extraocular motor nuclei, there is a debate as to its efficacy and utility in helping to identify safe entry zones for medullary incision in an intra-axial resection. We present two cases where we positively and negatively mapped the surface of the midbrain and rostral pons to assist in surgical decision-making. Both patients had gross total resections of cavernomas, and both awoke without any new onset extraocular motor deficits.

