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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Primary mucosa-associated lymphoid tissue lymphoma in the midbrain: A case report
Yong-Rui Zhao1, Rong-Hua Hu2, Rui Wu3
1Department of Radiation Oncology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Background:
Primary non-dural central nervous system mucosa-associated lymphoid tissue (MALT) lymphoma is a rare indolent B-cell lymphoma, with only a few reported cases worldwide.
Case Summary:
A 33-year-old man presented with a 5-mo history of left blepharoptosis and a 4-mo history of right limb numbness and weakness. Magnetic resonance imaging showed a significantly enhanced mass in the left midbrain. Subsequent positron emission tomography revealed that the lesion had increased glucose uptake. A stereotactic robotic biopsy supported a diagnosis of MALT lymphoma. Then he was treated with radiation therapy (30Gy/15F), which resulted in complete remission. We also review the literature on brain parenchymal-based MALT lymphoma, including the clinical presentation, treatment options, and outcomes.
Conclusion:
Although there is no consensus on the optimal treatment for this rare disease, patients can respond well when treated with radiotherapy alone.
