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Cutaneous onchocerciasis.

M J Maso1, R Kapila, R A Schwartz

  • 1Department of Dermatology, New Jersey Medical School, Newark 07103-2757.

International Journal of Dermatology
|November 1, 1987
PubMed
Summary
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Onchocerciasis, a parasitic skin disease, was diagnosed in a student from Cameroon. Treatment with ivermectin successfully eliminated microfilariae, highlighting its effectiveness for onchocerciasis.

Area of Science:

  • Medical Parasitology
  • Dermatology
  • Tropical Medicine

Background:

  • Onchocerciasis, also known as river blindness, is a neglected tropical disease caused by the filarial nematode Onchocerca volvulus.
  • It is endemic in many parts of sub-Saharan Africa, with Cameroon being a high-prevalence area.
  • Diagnosis typically involves identifying microfilariae in skin biopsies.

Observation:

  • A 22-year-old student from Cameroon presented with pruritic papules on his thighs.
  • Skin biopsy examination revealed the presence of microfilariae, confirming onchocerciasis.
  • The patient had no prior history of the disease.

Findings:

  • The patient was treated with ivermectin, an antiparasitic drug.
  • Ivermectin was well-tolerated by the patient.

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  • Post-treatment skin biopsies showed no detectable microfilariae, indicating successful treatment.

    • Implications:

    • This case underscores the importance of considering onchocerciasis in individuals from endemic regions presenting with compatible symptoms.
    • Ivermectin demonstrates efficacy and tolerability as a treatment for onchocerciasis.
    • Early diagnosis and treatment are crucial for managing onchocerciasis and preventing complications.