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Altered epigenetics at the center of NK-LGL leukemia

Marco Herling1,2, Linus Wahnschaffe1

  • 1University of Cologne.

Blood
|August 26, 2021
PubMed
Abstract

No abstract available in PubMed .

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Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
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