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Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

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Obesity and Poststroke Fatigue: A 2-Year Longitudinal Study.

Mengmeng Gu¹, Lulu Xiao², Jinjing Wang²

¹Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

Neurology and Therapy

|August 26, 2021

Summary

Obese patients experience less early poststroke fatigue (PSF) but are more prone to developing it later. Higher body mass index (BMI) in obese individuals correlates with slower fatigue recovery after stroke.

Keywords:

Body mass index Fatigue Severity Scale Obesity Poststroke fatigue

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Area of Science:

Neurology
Metabolic Disorders
Public Health

Background:

Obesity is a growing global health concern.
The relationship between obesity and poststroke fatigue (PSF) remains poorly understood.
Investigating BMI's impact on PSF is crucial for patient management.

Purpose of the Study:

To examine the association between body mass index (BMI) and the incidence of PSF.
To evaluate the effect of BMI on PSF recovery over 24 months.
To clarify the complex relationship between obesity and fatigue after ischemic stroke.

Main Methods:

Recruited 1026 ischemic stroke patients within 3 days of onset.
Assessed PSF using the Fatigue Severity Scale (FSS) at baseline and 6, 12, 24 months.
Employed multivariable logistic regression and mixed-effects models to analyze BMI and PSF data.

Main Results:

Obesity was linked to reduced risk of early PSF but increased risk of late PSF (6-24 months).
Higher BMI categories correlated with a slower decrease in FSS scores in the late fatigue stage.
Longitudinal analysis revealed slower fatigue symptom improvement in obese patients over time.

Conclusions:

Obese individuals have a lower likelihood of acute fatigue post-stroke.
Obesity is a significant risk factor for developing persistent and long-term fatigue after stroke.
BMI influences the trajectory of fatigue recovery, with higher BMI associated with poorer outcomes.