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Updated: Oct 22, 2025

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Neonatal Parotitis: A Case Report.

Ayush Gupta1,2, Tyler Kingdon2, Andrew McKernan2

  • 1Children's Hospital Of New Orleans, Department of Pediatric Emergency Medicine, New Orleans, Louisiana.

Clinical Practice and Cases in Emergency Medicine
|August 26, 2021
PubMed
Summary
This summary is machine-generated.

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Neonatal suppurative parotitis, a rare bacterial infection, presents as cheek swelling in newborns. Prompt diagnosis and antibiotic treatment are crucial for managing this condition in infants.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Neonatology

Background:

  • Acute suppurative parotitis is an uncommon condition in neonates, with Staphylococcus aureus being a frequent cause.
  • Limited literature exists, with only 32 reported cases in the last 35 years, highlighting its rarity.
  • This condition requires specialized management approaches tailored for the neonatal population.

Purpose of the Study:

  • To report a rare case of acute suppurative parotitis in a neonate.
  • To review existing literature on neonatal suppurative parotitis.
  • To emphasize the importance of considering this diagnosis in newborns with specific symptoms.

Main Methods:

  • A case report of a 14-day-old male infant presenting with right cheek swelling and redness.

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  • Clinical examination revealing purulent material in the oral cavity.
  • Hospitalization and treatment with five days of parenteral antibiotics followed by oral antibiotics.

    • Main Results:

    • The infant was diagnosed with neonatal suppurative parotitis.
    • Symptoms of swelling and redness improved with antibiotic therapy.
    • The patient was discharged in stable condition with oral antibiotics.

    Conclusions:

    • Neonatal suppurative parotitis should be suspected in newborns with erythematous pre-auricular masses, even without apparent predisposing factors.
    • Early recognition and appropriate antibiotic intervention are key to successful outcomes.
    • This case adds to the limited published data on this rare neonatal infection.