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Updated: Oct 22, 2025

Manual Muscle Testing: A Method of Measuring Extremity Muscle Strength Applied to Critically Ill Patients
Published on: April 12, 2011
19-year-old Woman with Intermittent Weakness
Garrett A Cavaliere1, Neeraja Murali2, Laura J Bontempo2
1University of Maryland Medical Center, Department of Emergency Medicine, Baltimore, Maryland.
Systemic weakness evaluation in the emergency department (ED) requires a systematic approach. This case highlights the diagnostic process for a young female with generalized weakness and electrolyte abnormalities.
Area of Science:
- Internal Medicine
- Emergency Medicine
- Clinical Diagnostics
Background:
- Systemic weakness is a frequent reason for emergency department (ED) visits.
- Effective patient assessment and workup are crucial for accurate diagnosis and treatment.
Purpose of the Study:
- To present a case study on the evaluation of generalized weakness and electrolyte abnormalities.
- To outline the differential diagnosis and diagnostic workup for such cases.
Main Methods:
- Case presentation of a 19-year-old female with generalized weakness and near syncope.
- Review of diagnostic studies and calculations for electrolyte derangements.
Main Results:
- The patient presented with global extremity weakness and multiple electrolyte abnormalities.
- The case details the diagnostic pathway leading to the final diagnosis.
Conclusions:
- A structured approach is essential for diagnosing weakness and electrolyte imbalances.
- Diagnostic studies and calculations are key to identifying the underlying cause.
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