Related Experiment Video
Updated: Aug 30, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
[Simultaneous bilateral renal cell adenocarcinoma. One-stage surgical treatment]
A Picciocchi1, D D'ugo, V Bruni
1Université catholique du Sacré-Coeur, Faculté de Médecine et Chirurgie, Hôpital Universitaire A. Gemelli, Roma, Italie.
Abstract:
Review of a very well documented case with a very complete iconography, and of the literature led to the following conclusions. First, it is preferable to treat these patients by a one-stage operation involving nephrectomy on one side and, if possible, conservative treatment to other kidney. Second, that the prognosis in synchronous bilateral renal cancer is much better than that of metachronous bilateral cancers (5-year survival 69% and 37.5% respectively), probably because the former are usually of low grade and early stage. This justifies the most audacious surgical tentatives and, in this respect, this paper is of very high interest.

